Acetic Acid

Acetic Acid

SCHEMBL4454694

CC(=O)[O-].CC(=O)[O-].c1ccc(C[Sn+2]Cc2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ALDH1A1 P00352 2/20 0.47
ALPL P05186 1/20 0.44
POLB P06746 1/20 0.44
ALPG P10696 1/20 0.44
LMNA P02545 2/20 0.44
AKR1B1 P15121 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
FNTA P49354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL384291 0.90 CES2 (0.43) CES2CES1ALDH1A1ALPLPOLB
SCHEMBL384289 0.90 CES2 (0.43) CES2CES1ALDH1A1ALPLPOLB
Fumaric Acid SCHEMBL385034 0.83 CES2 (0.45) CES2CES1ALDH1A1ALPLPOLB
Fumaric Acid SCHEMBL385037 0.83 CES2 (0.45) CES2CES1ALDH1A1ALPLPOLB
Propiolic Acid SCHEMBL30525601 0.82 CES2 (0.43) CES2CES1ALDH1A1ALPLPOLB
Adipic Acid SCHEMBL673647 0.82 HDAC1 (0.61) CES2CES1LMNAAKR1B1HDAC3
Acrylic Acid SCHEMBL4441136 0.82 CES2 (0.43) CES2CES1ALDH1A1ALPLPOLB
SCHEMBL384782 0.80 CES1 (0.52) CES2CES1ALDH1A1LMNAAKR1B1
SCHEMBL3764311 0.80 CES1 (0.52) CES2CES1ALDH1A1LMNAAKR1B1
SCHEMBL387267 0.78 CALM1 (0.47) ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
WO-2022124058-A1 POLYMER-METAL COMPLEX, TIRE, AND POLYMER ARTICLE 株式会社ブリヂストン 2022-06-16 WO disclosed
EP-1958980-B1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORP (JP) 2012-10-31 EP disclosed
US-20090270525-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORPORATION (JP) 2009-10-29 US disclosed
EP-1958980-A1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR Corporation (JP) 2008-08-20 EP disclosed
EP-0911352-A2 Baking coating and its use BAYER AG (DE) 1999-04-28 EP disclosed
US-4172159-A INPINGEMENT OF ORGANOTIN COMPOUND SAINT-GOBAIN INDUSTRIES (FR) 1979-10-23 US disclosed