Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.72 |
| ▸ | HTR2B | P41595 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.62 |
| ▸ | AR | P10275 | 8/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diflucortolone 21-Valerate SCHEMBL13157 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL1021717 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL11243011 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL9388448 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL13158 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL3015 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL2790985 | 0.99 | PGR (0.73) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL18113135 | 0.98 | PGR (0.72) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL2353254 | 0.98 | PGR (0.72) | PGRNR1I2HTR2BHIF1AAR | |
| Diflucortolone 21-Valerate SCHEMBL20571795 | 0.98 | PGR (0.72) | PGRNR1I2HTR2BHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312646-A1 | OPTICAL DETECTION OF SEIZURE, A PRE-SEIZURE STATE, AND CEREBRAL EDEMA AND OPTICAL FIBER DETECTION OF THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-12-17 | — | — | US | disclosed |