Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450060 | 0.90 | LMNA (0.35) | LMNATDP1 | |
| SCHEMBL3682761 | 0.84 | LMNA (0.34) | LMNATDP1ALDH1A1 | |
| SCHEMBL4461505 | 0.82 | LMNA (0.37) | LMNAALDH1A1 | |
| SCHEMBL4457981 | 0.82 | TDP1 (0.31) | TDP1 | |
| SCHEMBL98468 | 0.81 | LMNA (0.40) | LMNATDP1ALDH1A1 | |
| SCHEMBL96149 | 0.80 | LMNA (0.42) | LMNATDP1ALDH1A1 | |
| SCHEMBL30205727 | 0.80 | LMNA (0.42) | LMNATDP1ALDH1A1 | |
| SCHEMBL30205673 | 0.80 | LMNA (0.42) | LMNATDP1ALDH1A1 | |
| SCHEMBL30205627 | 0.80 | LMNA (0.42) | LMNATDP1ALDH1A1 | |
| SCHEMBL30205721 | 0.80 | LMNA (0.42) | LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680469-B1 | SILICA-FILLED ELASTOMERIC COMPOUNDS | LANXESS INC (CA) | 2009-01-07 | — | — | EP | claimed |
| CN-1894329-A | Butyl rubber composition for tire treads | LANXESS INC (CA) | 2007-01-10 | — | — | CN | disclosed |