SCHEMBL4450060

SCHEMBL4450060

CCC(=O)SCCC[Si](OC)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454853 0.90 LMNA (0.32) LMNATDP1
SCHEMBL3684598 0.85 LMNA (0.37) LMNA
SCHEMBL4453725 0.83 LMNA (0.40) LMNA
SCHEMBL4457552 0.82 TDP1 (0.30) TDP1
SCHEMBL98569 0.82 LMNA (0.42) LMNATDP1
SCHEMBL3682359 0.82 CYP2C19 (0.39) LMNA
SCHEMBL16547102 0.81 MGAM (0.35) LMNA
SCHEMBL21049771 0.80 LMNA (0.45) LMNATDP1
SCHEMBL21049772 0.80 LMNA (0.45) LMNATDP1
SCHEMBL97747 0.80 LMNA (0.45) LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116285400-B Porous carbon polymer/block copolymer modified asphalt, and preparation method and application thereof 山东金衢设计咨询集团有限公司 2024-04-02 CN claimed
CN-116285400-A Porous carbon polymer/block copolymer modified asphalt, and preparation method and application thereof 山东交通学院 2023-06-23 CN claimed
CN-108794830-B Rubber composition, vulcanized rubber, and preparation method and application thereof 中国石油化工股份有限公司 2021-07-02 CN claimed
CN-108017728-B Rubber composition, modified rubber with self-healing function and preparation method and application thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-102947379-B Tire rubber composition and pneumatic tire using same YOKOHAMA RUBBER CO LTD 2014-04-30 CN claimed
CN-102947379-A Tire rubber composition and pneumatic tire using same YOKOHAMA RUBBER CO LTD 2013-02-27 CN claimed
EP-1680469-B1 SILICA-FILLED ELASTOMERIC COMPOUNDS LANXESS INC (CA) 2009-01-07 EP claimed
EP-4748881-A1 COMPOUNDING AGENT FOR DIENE RUBBERS AND RUBBER COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-05-27 EP disclosed
CN-119768462-B Rubber composition 横滨橡胶株式会社 2026-05-15 CN disclosed
US-20260103590-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2026-04-16 US disclosed
US-20260103583-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2026-04-16 US disclosed
US-20260098111-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2026-04-09 US disclosed
US-20260071059-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE TOYO TIRE CORPORATION (JP) 2026-03-12 US disclosed
US-20020099118-A1 For use in tires, shoe soles WITCO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2002-07-25 US disclosed
US-6414061-B1 CURABLE MIXTURE CROMPTON CORPORATION 2002-07-02 US disclosed
US-20020055646-A1 Reacting a mercaptosilane and a monoacid anhydride corresponding to a thioester group present in the desired product, or reacting alkali salt of a mercaptosilane with an acid anhydride or acid halide or transesterification WITCO CORPORATION 2002-05-09 US disclosed
US-20020055568-A1 3-(acylmercapto)propyltrialkoxy- or trihydroxysilane WITCO CORPORATION 2002-05-09 US disclosed
US-20020055564-A1 Sulfur silane coupling agents which are latent WITCO CORPORATION 2002-05-09 US disclosed
EP-0958298-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS WITCO CORPORATION (US) 1999-11-24 EP disclosed
WO-1999009036-A1 BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS OSI SPECIALTIES, INC. (US) 1999-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071059-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE PTGES, DGKG, DGKA LMNA 1986/4885TDP1 1432/4885
US-20260103583-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE GYS1, IRS1, GK LMNA 1733/4885TDP1 1064/4885
US-20260103590-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE GYS1, FAM83E, CSDE1 LMNA 1628/4885TDP1 76/4885
US-20260098111-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE GK, FFAR1, ELOVL1 LMNA 1543/4885TDP1 1109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.