Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455720 | 0.86 | NPSR1 (0.48) | NPSR1EPHX2ALDH1A1ATMHPGD | |
| SCHEMBL692776 | 0.84 | NPSR1 (0.63) | NPSR1EPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL6742511 | 0.83 | NPSR1 (0.44) | NPSR1EPHX2ALDH1A1ATMHPGD | |
| SCHEMBL29135724 | 0.82 | NPSR1 (0.55) | NPSR1EPHX2ALDH1A1HCAR2 | |
| SCHEMBL6452242 | 0.80 | EPHX2 (0.52) | NPSR1EPHX2ALDH1A1ATMMEN1 | |
| SCHEMBL29135604 | 0.78 | NPSR1 (0.60) | NPSR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13084353 | 0.78 | NPSR1 (0.60) | NPSR1EPHX2ALDH1A1TSHR | |
| SCHEMBL691868 | 0.78 | NPSR1 (0.60) | NPSR1EPHX2ALDH1A1TSHR | |
| SCHEMBL30352838 | 0.78 | NPSR1 (0.43) | NPSR1EPHX2ALDH1A1HCAR2TSHR | |
| SCHEMBL1733349 | 0.78 | NPSR1 (0.43) | NPSR1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099326-A1 | FLUORINE-CONTAINING ADAMANTANE DERIVATIVE, FLUORINE-CONTAINING ADAMANTANE DERIVATIVE HAVING POLYMERIZABLE GROUP, RESIN COMPOSITION CONTAINING THE SAME, AND ANTIREFLECTION FILM | IDEMITSU KOSAN CO., LTD. (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-2014639-A1 | FLUORINE-CONTAINING ADAMANTANE DERIVATIVE, FLUORINE-CONTAINING ADAMANTANE DERIVATIVE HAVING POLYMERIZABLE GROUP, RESIN COMPOSITION CONTAINING THE SAME, AND ANTIREFLECTION FILM | Idemitsu Kosan Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099326-A1 | FLUORINE-CONTAINING ADAMANTANE DERIVATIVE, FLUORINE-CONTAINING ADAMANTANE DERIVATIVE HAVING POLYMERIZABLE GROUP, RESIN COMPOSITION CONTAINING THE SAME, AND ANTIREFLECTION FILM | ADGRF1, RFT1, AFF1 | NPSR1 897/4885EPHX2 1783/4885ALDH1A1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.