Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13084353 | 1.00 | NPSR1 (0.60) | NPSR1EPHX2NAAAEPHX1ALDH1A1 | |
| SCHEMBL25713906 | 0.94 | NPSR1 (0.55) | NPSR1EPHX2NAAAEPHX1ALDH1A1 | |
| SCHEMBL692776 | 0.94 | NPSR1 (0.63) | NPSR1EPHX2ALDH1A1 | |
| SCHEMBL25776354 | 0.89 | EPHX2 (0.58) | NPSR1EPHX2NAAAALDH1A1 | |
| SCHEMBL692491 | 0.87 | NPSR1 (0.67) | NPSR1ALDH1A1 | |
| SCHEMBL7459150 | 0.85 | NPSR1 (0.57) | NPSR1EPHX2ALDH1A1TSHR | |
| SCHEMBL6452242 | 0.83 | EPHX2 (0.52) | NPSR1EPHX2ALDH1A1 | |
| SCHEMBL15858285 | 0.83 | NPSR1 (0.49) | NPSR1EPHX2ALDH1A1 | |
| SCHEMBL7797332 | 0.82 | NPSR1 (0.55) | NPSR1EPHX2ALDH1A1TSHR | |
| SCHEMBL7797293 | 0.82 | NPSR1 (0.55) | NPSR1EPHX2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421904-B1 | PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD | GRACE W R & CO (US) | 2015-06-24 | — | — | EP | disclosed |
| US-8288304-B2 | Procatalyst composition with adamantane and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-10-16 | — | — | US | disclosed |
| EP-2421904-A1 | PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD | Dow Global Technologies LLC (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123775-A1 | PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20100273966-A1 | Procatalyst Composition with Adamantane and Method | W. R. GRACE & CO.-CONN. | 2010-10-28 | — | — | US | disclosed |