Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.81 |
| ▸ | CCKAR | P32238 | 1/20 | 0.81 |
| ▸ | HTR5A | P47898 | 1/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626236 | 1.00 | HTR1A (0.81) | HTR1AADORA3CCKARHTR5ARAB9A | |
| SCHEMBL4454995 | 1.00 | HTR1A (0.81) | HTR1AADORA3CCKARHTR5ARAB9A | |
| SCHEMBL13626452 | 0.90 | HTR1A (1.00) | HTR1AADORA3CCKARHTR5AMEN1 | |
| SCHEMBL4318956 | 0.90 | HTR1A (1.00) | HTR1AADORA3CCKARHTR5AMEN1 | |
| SCHEMBL4311261 | 0.85 | HTR1A (0.61) | HTR1AADORA3CCKARHTR5AMEN1 | |
| SCHEMBL13626630 | 0.85 | HTR1A (0.61) | HTR1AADORA3CCKARHTR5AMEN1 | |
| SCHEMBL13172256 | 0.82 | HTR1A (0.63) | HTR1AADORA3CCKARHTR5ARAB9A | |
| SCHEMBL13626451 | 0.77 | HTR1A (0.51) | HTR1AADORA3CCKARHTR5A | |
| SCHEMBL14082867 | 0.76 | PTPN1 (0.67) | RAB9ANPC1MEN1POLBKMT2A | |
| SCHEMBL4323726 | 0.76 | HTR1A (0.74) | HTR1AADORA3CCKARHTR5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |