Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CCKAR | P32238 | 1/20 | 0.51 |
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557886 | 0.91 | HTR1A (0.64) | HTR1AADORA3CCKARHTR5ANAAA | |
| SCHEMBL4454995 | 0.77 | HTR1A (0.81) | HTR1AADORA3CCKARHTR5A | |
| SCHEMBL13626236 | 0.77 | HTR1A (0.81) | HTR1AADORA3CCKARHTR5A | |
| SCHEMBL4454997 | 0.77 | HTR1A (0.81) | HTR1AADORA3CCKARHTR5A | |
| SCHEMBL18373495 | 0.75 | HDAC3 (0.47) | LMNAMGLLFAAHL3MBTL1 | |
| SCHEMBL27484667 | 0.72 | MGLL (0.56) | MGLL | |
| SCHEMBL28404876 | 0.71 | HSD17B3 (0.56) | — | |
| SCHEMBL28039309 | 0.69 | CES2 (0.60) | — | |
| SCHEMBL31418296 | 0.69 | MGLL (0.57) | MGLLFAAH | |
| SCHEMBL19003116 | 0.69 | KMT2A (0.44) | HTR1AADORA3CCKARHTR5ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |