Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783891 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KCNN4KCNA5ADRA1AHCRTR1 | |
| SCHEMBL4451787 | 0.89 | HCRTR1 (0.40) | ALDH1A1ADRA1AHCRTR1GAAMEN1 | |
| SCHEMBL13783801 | 0.89 | HCRTR1 (0.40) | ALDH1A1ADRA1AHCRTR1GAAMEN1 | |
| SCHEMBL4451792 | 0.89 | HCRTR1 (0.40) | ALDH1A1ADRA1AHCRTR1GAAMEN1 | |
| SCHEMBL13783960 | 0.87 | NPC1 (0.41) | ALDH1A1ADRA1AHCRTR1GAAMEN1 | |
| SCHEMBL4460551 | 0.86 | KMT2A (0.52) | ALDH1A1ADRA1AHCRTR1GAAMEN1 | |
| SCHEMBL4460557 | 0.86 | KMT2A (0.52) | ALDH1A1ADRA1AHCRTR1GAAMEN1 | |
| SCHEMBL4316894 | 0.83 | NPSR1 (0.56) | ALDH1A1GAAKMT2ANPC1RAB9A | |
| SCHEMBL4316889 | 0.83 | NPSR1 (0.56) | ALDH1A1GAAKMT2ANPC1RAB9A | |
| SCHEMBL13784018 | 0.83 | NPSR1 (0.56) | ALDH1A1GAAKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |