Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784018 | 1.00 | NPSR1 (0.56) | NPSR1GAATSHRTDP1MAPK1 | |
| SCHEMBL4316894 | 1.00 | NPSR1 (0.56) | NPSR1GAATSHRTDP1MAPK1 | |
| SCHEMBL13783800 | 0.91 | KMT2A (0.49) | NPSR1GAATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4316447 | 0.91 | KMT2A (0.49) | NPSR1GAATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL4316449 | 0.91 | KMT2A (0.49) | NPSR1GAATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL13783960 | 0.85 | NPC1 (0.41) | NPSR1GAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4451828 | 0.84 | FPR1 (0.46) | NPSR1GAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL13783918 | 0.84 | FPR1 (0.46) | NPSR1GAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4451822 | 0.84 | FPR1 (0.46) | NPSR1GAASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL13783891 | 0.83 | ALDH1A1 (0.44) | NPSR1GAASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |