Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 12/20 | 0.36 |
| ▸ | FAAH | O00519 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919445 | 0.82 | HSP90AA1 (0.58) | HSP90AA1MGLLFAAHHTTALDH1A1 | |
| SCHEMBL4457947 | 0.79 | TLR9 (0.44) | HSP90AA1MGLLFAAHALDH1A1PKM | |
| SCHEMBL4899648 | 0.78 | POLB (0.56) | HTTALDH1A1PKMPOLBMAPT | |
| SCHEMBL4443452 | 0.77 | TLR9 (0.59) | HSP90AA1MGLLFAAHALDH1A1PKM | |
| SCHEMBL4448542 | 0.76 | TLR9 (0.44) | HSP90AA1MGLLFAAHHTTALDH1A1 | |
| SCHEMBL4443144 | 0.75 | MGLL (0.40) | HSP90AA1MGLLFAAHALDH1A1PKM | |
| SCHEMBL4443303 | 0.74 | MGLL (0.56) | HSP90AA1MGLLFAAHHTTALDH1A1 | |
| SCHEMBL4844501 | 0.74 | HSP90AA1 (0.45) | HSP90AA1MGLLFAAHHTTALDH1A1 | |
| SCHEMBL4443401 | 0.70 | MGLL (0.45) | HSP90AA1MGLLFAAHALDH1A1PKM | |
| SCHEMBL4443314 | 0.69 | MGLL (0.41) | HSP90AA1MGLLFAAHALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557151-B2 | Rubber composition comprising an itaconimidomaleimide | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2009-07-07 | — | — | US | disclosed |
| US-20090036579-A1 | Rubber Composition Comprising an Itaconimidomaleimide | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2009-02-05 | — | — | US | disclosed |
| EP-1863871-A1 | RUBBER COMPOSITION COMPRISING AN ITACONIMIDO-MALEIMIDE | Societe de Technologie Michelin STM (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099985-A1 | RUBBER COMPOSITION COMPRISING AN ITACONIMIDO-MALEIMIDE | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2006-09-28 | — | — | WO | disclosed |