Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 10/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CASP6 | P55212 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448542 | 0.94 | TLR9 (0.44) | TLR9MGLLFAAHKMT2ACASP6 | |
| SCHEMBL4443452 | 0.89 | TLR9 (0.59) | TLR9MGLLFAAHKMT2ACASP6 | |
| SCHEMBL4443401 | 0.80 | MGLL (0.45) | TLR9MGLLFAAHKMT2ACASP6 | |
| SCHEMBL4899648 | 0.79 | POLB (0.56) | KMT2ACASP6TDP1CASP3SENP8 | |
| SCHEMBL4455256 | 0.79 | HSP90AA1 (0.43) | TLR9MGLLFAAHKMT2AALDH1A1 | |
| SCHEMBL5077484 | 0.79 | TLR9 (0.68) | TLR9MGLLFAAHTDP1ALDH1A1 | |
| SCHEMBL31180023 | 0.79 | TLR9 (0.68) | TLR9MGLLFAAHTDP1ALDH1A1 | |
| SCHEMBL4445231 | 0.75 | MGLL (0.39) | TLR9MGLLKMT2ACASP6TDP1 | |
| SCHEMBL4443303 | 0.75 | MGLL (0.56) | MGLLFAAHKMT2ATDP1MEN1 | |
| SCHEMBL5188759 | 0.72 | GAA (0.41) | TLR9KMT2ACASP6TDP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557151-B2 | Rubber composition comprising an itaconimidomaleimide | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2009-07-07 | — | — | US | disclosed |
| US-20090036579-A1 | Rubber Composition Comprising an Itaconimidomaleimide | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2009-02-05 | — | — | US | disclosed |
| EP-1863871-A1 | RUBBER COMPOSITION COMPRISING AN ITACONIMIDO-MALEIMIDE | Societe de Technologie Michelin STM (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099985-A1 | RUBBER COMPOSITION COMPRISING AN ITACONIMIDO-MALEIMIDE | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2006-09-28 | — | — | WO | disclosed |