⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220383 | 0.85 | — | — | |
| Pyrimidine SCHEMBL12393457 | 0.67 | — | — | |
| Pyrimidine SCHEMBL28014711 | 0.67 | — | — | |
| Pyridine SCHEMBL483965 | 0.66 | TSHR (0.50) | — | |
| SCHEMBL73936 | 0.60 | — | — | |
| Pyrimidine SCHEMBL1846 | 0.60 | — | — | |
| Pyrimidine SCHEMBL10646 | 0.60 | TSHR (0.50) | — | |
| Pyrimidine SCHEMBL19437633 | 0.60 | TSHR (0.50) | — | |
| Pyrimidine SCHEMBL383109 | 0.57 | — | — | |
| Pyrimidine SCHEMBL1662110 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528252-B2 | Derivatives of triazoly-imidazopyridine useful as ligands of the adenosine A2a receptor and their use as medicaments | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-05-05 | — | — | US | disclosed |
| US-20070249638-A1 | Derivatives of triazoly-imidazopyridine and of the triazolypurines useful as ligands of the adenosine A2a receptor and their use as medicaments | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-10-25 | — | — | US | disclosed |
| US-7230102-B2 | Derivatives of triazolyl-imidazopyridine and of the triazolylpurines useful as ligandsof the adenosine a2a receptor and their use as medicaments | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-06-12 | — | — | US | disclosed |
| CN-1271070-C | As adenosine A2αDerivatives of triazolyl-imidazopyridine and triazolylpurine as ligands for receptors and their use as medicaments | SIGMA TAU IND FAMACEUTICHE RIU (IT) | 2006-08-23 | — | — | CN | disclosed |
| EP-1412354-B1 | DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A 2a? RECEPTOR AND THEIR USE AS MEDICAMENTS | SIGMA TAU IND FARMACEUTI (IT) | 2006-05-10 | — | — | EP | disclosed |
| US-20040204428-A1 | Derivatives of triazolyl-imidazopyridine and of the triazolylpurines useful as ligandsof the adenosine a2a receptor and their use as medicaments | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-10-14 | — | — | US | disclosed |
| CN-1525974-A | As adenosine A2aDerivatives of triazolyl-imidazopyridine and triazolylpurine as ligands for receptors and their use as medicaments | ϣ��������ҩ��ҵ��˾ | 2004-09-01 | — | — | CN | disclosed |
| CN-1154494-C | Adenosine A3 receptor modulators | ��¿��о���˾ | 2004-06-23 | — | — | CN | disclosed |
| EP-1412354-A1 | DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A 2a? RECEPTOR AND THEIR USE AS MEDICAMENTS | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011864-A1 | DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-02-13 | — | — | WO | disclosed |
| CN-1303289-A | Adenosine A3 receptor modulators | MEDCO RES INC (US) | 2001-07-11 | — | — | CN | disclosed |