Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468304 | 1.00 | HCRTR1 (0.43) | HCRTR1HCRTR2ACEELANECTSS | |
| SCHEMBL4455606 | 1.00 | HCRTR1 (0.43) | HCRTR1HCRTR2ACEELANECTSS | |
| SCHEMBL4458293 | 0.86 | ACE (0.44) | HCRTR1HCRTR2ACEELANECTSS | |
| SCHEMBL4455505 | 0.86 | ACE (0.44) | HCRTR1HCRTR2ACEELANECTSS | |
| SCHEMBL4455495 | 0.86 | ACE (0.44) | HCRTR1HCRTR2ACEELANECTSS | |
| SCHEMBL4458302 | 0.86 | ACE (0.44) | HCRTR1HCRTR2ACEELANECTSS | |
| SCHEMBL8208603 | 0.79 | ELANE (0.56) | HCRTR1HCRTR2ACEELANE | |
| SCHEMBL4452899 | 0.79 | NPC1 (0.45) | ELANECTSSTSHRLMNA | |
| SCHEMBL4452895 | 0.79 | NPC1 (0.45) | ELANECTSSTSHRLMNA | |
| SCHEMBL4455577 | 0.74 | CTSS (0.43) | ELANECTSSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |