Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455625 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2APOLBKCNJ6KCNJ5 | |
| SCHEMBL13783791 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2APOLBKCNJ6KCNJ5 | |
| SCHEMBL4457337 | 0.86 | CNR1 (0.41) | KMT2AKCNJ6KCNJ3MEN1GAA | |
| SCHEMBL4457335 | 0.86 | CNR1 (0.41) | KMT2AKCNJ6KCNJ3MEN1GAA | |
| SCHEMBL13783790 | 0.86 | CNR1 (0.41) | KMT2AKCNJ6KCNJ3MEN1GAA | |
| SCHEMBL13783917 | 0.79 | CNR1 (0.41) | ALDH1A1KMT2APOLBMEN1GAA | |
| SCHEMBL4456054 | 0.77 | MEN1 (0.48) | ALDH1A1KMT2APOLBMEN1NPC1 | |
| SCHEMBL4456059 | 0.77 | MEN1 (0.48) | ALDH1A1KMT2APOLBMEN1NPC1 | |
| SCHEMBL4458275 | 0.75 | CCR3 (0.47) | ALDH1A1KMT2AMEN1GAANPC1 | |
| SCHEMBL13783977 | 0.75 | CCR3 (0.47) | ALDH1A1KMT2AMEN1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |