Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | PHGDH | O43175 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453436 | 0.88 | HPGD (0.70) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4455962 | 0.87 | MAPT (0.68) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4453467 | 0.82 | MAPT (0.65) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4343474 | 0.80 | KDM4E (0.68) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13886982 | 0.77 | PHGDH (0.77) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4455860 | 0.77 | PHGDH (0.77) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28369669 | 0.76 | PHGDH (0.69) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28373194 | 0.76 | PHGDH (0.81) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28373192 | 0.76 | PHGDH (0.81) | HPGDKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28369671 | 0.76 | PHGDH (0.69) | HPGDKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |