Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455852 | 0.87 | HPGD (0.66) | MAPTHPGDKDM4EGAAALDH1A1 | |
| SCHEMBL4343474 | 0.86 | KDM4E (0.68) | MAPTHPGDKDM4EGAACYP1A2 | |
| SCHEMBL4453467 | 0.82 | MAPT (0.65) | MAPTHPGDKDM4EGAAALDH1A1 | |
| SCHEMBL12417203 | 0.81 | MAPT (0.74) | MAPTHPGDKDM4EGAACYP1A2 | |
| SCHEMBL13611595 | 0.78 | ALDH1A1 (0.75) | MAPTHPGDKDM4EGAACYP1A2 | |
| SCHEMBL4455965 | 0.78 | ALDH1A1 (0.75) | MAPTHPGDKDM4EGAACYP1A2 | |
| SCHEMBL13611475 | 0.77 | MAPT (0.71) | MAPTHPGDKDM4EGAACYP1A2 | |
| SCHEMBL4328162 | 0.76 | MAPT (0.79) | MAPTHPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL4328166 | 0.76 | MAPT (0.79) | MAPTHPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL4462856 | 0.75 | PRMT5 (0.67) | MAPTHPGDKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |