SCHEMBL4456129

SCHEMBL4456129

CCCC(OCC)C(CS)C(=O)[O-].CCCC(OCC)C(CS)C(=O)[O-].CCCC[Sn+2]CCCC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CYP3A4 P08684 2/20 0.33
TSHR P16473 2/20 0.33
NFKB1 P19838 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
CA2 P00918 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10579851 0.87 CYP3A4 (0.39) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL3520045 0.76 CA1 (0.38) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL9245546 0.74 CA1 (0.41) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL5078696 0.74 CA2 (0.37) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL28166168 0.74 CHRM1 (0.39) CA2
SCHEMBL11878759 0.71 CA2 (0.55) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL3520573 0.71 CA1 (0.40) CA1CA2
SCHEMBL11882480 0.71 CA1 (0.50) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL3518074 0.70 CA2 (0.44) CA1CYP3A4TSHRNFKB1NPSR1
SCHEMBL9856766 0.69 CA1 (0.42) CA1CYP3A4TSHRNFKB1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8637629-B2 High moisture vapor transmissive polyurethanes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-01-28 US claimed
WO-2009108678-A1 HIGH MOISTURE VAPOR TRANSMISSIVE POLYURETHANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-09-03 WO claimed
US-20080176083-A1 High Moisture Vapor Transmissive Polyurethanes NOVEON, INC. (US) 2008-07-24 US claimed
WO-2008089163-A1 HIGH MOISTURE VAPOR TRANSMISSIVE POLYURETHANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2008-07-24 WO claimed
US-20250188216-A1 FLUORINATED THERMOPLASTIC POLYURETHANE ABIOMED, INC. (US) 2025-06-12 US disclosed
EP-3212688-B1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MAT INC (US) 2022-04-13 EP disclosed
US-10905646-B2 Thermoplastic polyurethane film for delivery of active agents to skin surfaces LUBRIZOL ADVANCED MATERIALS, INC. 2021-02-02 US disclosed
US-20170319462-A1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MATERIALS, INC. 2017-11-09 US disclosed
EP-3212688-A2 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES Lubrizol Advanced Materials, Inc. (US) 2017-09-06 EP disclosed
WO-2016069396-A2 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-05-06 WO disclosed
US-8637629-B2 High moisture vapor transmissive polyurethanes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2014-01-28 US disclosed
WO-2009108678-A1 HIGH MOISTURE VAPOR TRANSMISSIVE POLYURETHANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2009-09-03 WO disclosed
EP-0796899-B1 Resin composition and molded article of the same KURARAY CO (JP) 2002-10-16 EP disclosed
EP-0974608-B1 Thermoplastic polyurethanes, elastic fibers therefrom, and method for producing the fibers KURARAY CO (JP) 2002-10-09 EP disclosed
US-6197915-B1 CONDENSATION POLYMERIZATION OF POLYESTER POLYOL, POLYETHER POLYOL AND DIISOCYANATE; HEAT RESISTANCE, WATERPROOFING; MELT SPINNING KURARAY CO., LTD. (JP) 2001-03-06 US disclosed
EP-0974608-A1 Thermoplastic polyurethanes, elastic fibers therefrom, and method for producing the fibers Kuraray Co., Ltd. (JP) 2000-01-26 EP disclosed
US-5912193-A RESILIENT POLYESTERURETHANE COPOLYMERS FORMED INTO FIBERS BY MELT SPINNING KURARAY CO., LTD. (JP) 1999-06-15 US disclosed
US-5859131-A BLEND OF THERMOPLASTIC POLYURETHANE, HYDROGENATED DIOLEFIN-OLEFIN COPOLYMER WITH HYDROXYLATED END GROUP, AND POLYACETAL RESIN; IMPACT AND TENSILE STRENGTH; COLD RESISTANCE KURARAY CO. LTD. (JP) 1999-01-12 US disclosed
US-5780573-A MADE WITH ORGANIC DIISOCYANATE, CHAIN EXTENDER AND POLYESTER-POLYOL THAT SATISIFIES SPECIFIED REQUIREMENTS KURARAY CO., LTD. (JP) 1998-07-14 US disclosed
EP-0748829-A1 Thermoplastic polyurethanes and molded articles comprising them KURARAY CO., LTD. (JP) 1996-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10905646-B2 Thermoplastic polyurethane film for delivery of active agents to skin surfaces DNER, CUTA, PUF60 CA1 1248/4885CYP3A4 1344/4885TSHR 2283/4885
US-20170319462-A1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES DNER, CUTA, PUF60 CA1 1248/4885CYP3A4 1344/4885TSHR 2283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.