SCHEMBL4456397

SCHEMBL4456397

CCCCOCc1nnc(COCCCC)s1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.40
TSHR P16473 3/20 0.38
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 5/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 1/20 0.36
P2RX7 Q99572 1/20 0.36
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14770084 0.71 POLB (0.56) RAB9AHSD17B10ALDH1A1SMN1; SMN2POLB
SCHEMBL8957587 0.68 ALDH1A1 (0.50) HSD17B10ALDH1A1SMN1; SMN2POLBMAPT
SCHEMBL6406054 0.67 ALDH1A1 (0.69) RAB9ATSHRHSD17B10ALDH1A1SMN1; SMN2
SCHEMBL15167 0.66
SCHEMBL8600029 0.66 TSHR (0.71) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL439119 0.66 TSHR (0.71) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL28748446 0.66 TSHR (0.71) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL6707479 0.65 TSHR (0.43) TSHRALDH1A1ADRB2ADRB1ADRB3
SCHEMBL12981791 0.65
SCHEMBL22368217 0.65 ALDH1A1 (0.73) RAB9ATSHRHSD17B10ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773523-A STORAGE STABILITY R.T. VANDERBILT COMPANY, INC. (US) 1998-06-30 US claimed
EP-0832922-A2 Composite curing compositions for the halogen containing polymers R.T. VANDERBILT COMPANY, Inc. (US) 1998-04-01 EP claimed
EP-0779331-A2 1,3,4-Thiadiazole ether curing systems for chlorine containing polymers R.T. VANDERBILT COMPANY, Inc. (US) 1997-06-18 EP claimed
EP-1539829-B1 CHLORINATED POLYOLEFINS AND PROCESS FOR THEIR PRODUCTION SHOWA DENKO KK (JP) 2009-11-11 EP disclosed
US-7354975-B2 Chlorinated polyolefins and process for their production SHOWA DENKO K.K. (JP) 2008-04-08 US disclosed
US-20060047087-A1 Chlorinated polyolefins and process for their production SHOWA DENKO K.K. (JP) 2006-03-02 US disclosed
US-6815478-B2 ZEOLITE COMPOUND, A VULCANIZING AGENT, AND AN ORGANIC VULCANIZATION ACCELERATOR DAISO CO., LTD. (JP) 2004-11-09 US disclosed
US-20030153652-A1 Chlorine-containing polymer vulcanizing composition DAISO CO., LTD (JP) 2003-08-14 US disclosed
US-6500884-B1 STORAGE STABLE BLEND OF A ZEOLITE, A VULCANIZING AGENT SELECTED FROM THE GROUP CONSISTING OF A MERCAPTOTRIAZINE COMPOUND AND A THIADIAZOLE COMPOUND, AND AN ORGANIC VULCANIZATION ACCELERATOR DAISO CO., LTD. (JP) 2002-12-31 US disclosed