SCHEMBL4456567

SCHEMBL4456567

CCOc1ccc(-c2nc(Cl)nc(Cl)n2)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
S1PR1 P21453 1/20 0.42
S1PR3 Q99500 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 3/20 0.41
MAPT P10636 4/20 0.40
HPGD P15428 4/20 0.40
ALDH1A1 P00352 4/20 0.40
TSHR P16473 4/20 0.40
LMNA P02545 4/20 0.40
ALOX12 P18054 1/20 0.40
NTSR1 P30989 1/20 0.40
CCR6 P51684 1/20 0.40
MCL1 Q07820 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 3/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
HTT P42858 2/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30416160 0.82 MAPT (0.48) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL11406614 0.82 MAPT (0.48) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL268758 0.81 L3MBTL1 (0.43) L3MBTL1S1PR1S1PR3MEN1KMT2A
SCHEMBL29366362 0.81 L3MBTL1 (0.43) L3MBTL1S1PR1S1PR3MEN1KMT2A
SCHEMBL10893667 0.79 ALDH1A1 (0.50) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL30620880 0.79 MAPT (0.48) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL6031052 0.79 MAPT (0.48) L3MBTL1MEN1KMT2AMAPTHPGD
SCHEMBL29378631 0.77 ALDH1A1 (0.54) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL50817 0.77 ALDH1A1 (0.54) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL4357684 0.76 AGPAT2 (0.59) L3MBTL1MEN1KMT2AHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235819-B1 Process to scavenge amines in polymeric compounds by treatment with triazine derivatives and compositions therefrom BRIDGESTONE CORPORATION (JP) 2001-05-22 US claimed
US-6063873-A RUBBER TREAD STOCK COMPRISING A VULCANIZABLE COMPOSITION FREE OF METAL REINFORCEMENT, AND A TRIAZINE COMPOUND OF GIVEN FORMULA WHICH ACTS AS AN AMINE SCAVENGER WITHOUT HAVING A DELETERIOUS EFFECT UPON THE VULCANIZABLE COMPOSITION BRIDGESTONE CORPORATION (JP) 2000-05-16 US claimed
EP-0927740-A2 Process to scavenge amines in polymeric compounds by treatment with triazine derivates, and compositions therefrom Bridgestone Corporation (JP) 1999-07-07 EP claimed
EP-0927744-A2 Process to scavenge amines in polymeric compounds by treatment with triazine derivates, and compositions therefrom Bridgestone Corporation (JP) 1999-07-07 EP claimed
CN-110662738-A Triazine peroxide derivative and polymerizable composition containing same 日油株式会社 2020-01-07 CN disclosed
EP-1846250-B1 LITHOGRAPHIC SUBSTRATES AND LITHOGRAPHIC PRINTING PLATES KODAK GRAPHIC COMM GMBH (DE) 2012-10-10 EP disclosed
US-7524613-B2 Material for the treatment of lithographic substrates and lithographic printing plates KODAK GRAPHIC COMMUNICATIONS, GMBH (DE) 2009-04-28 US disclosed
US-20080206666-A1 Material For The Treatment Of Lithographic Substrates And Lithographic Printing Plates KODAK POLYCHROME GRAPHICS, GMBH (DE) 2008-08-28 US disclosed
EP-0927740-A2 Process to scavenge amines in polymeric compounds by treatment with triazine derivates, and compositions therefrom Bridgestone Corporation (JP) 1999-07-07 EP disclosed
EP-0927744-A2 Process to scavenge amines in polymeric compounds by treatment with triazine derivates, and compositions therefrom Bridgestone Corporation (JP) 1999-07-07 EP disclosed