SCHEMBL4456664

SCHEMBL4456664

Nc1cc(Oc2ccccc2)c(O)c(O)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TTR P02766 2/20 0.42
MAOB P27338 1/20 0.41
LTA4H P09960 2/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
MAOA P21397 1/20 0.41
CTNNB1 P35222 1/20 0.41
NCOA1 Q15788 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
CAMK2A Q9UQM7 1/20 0.38
ADORA2A P29274 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852898 0.79 CYP1A2 (0.49) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL679994 0.79 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL30561268 0.79 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL10783275 0.76 ADORA2A (0.44) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL6653392 0.76 CYP1A2 (0.49) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL9768120 0.75 LTA4H (0.55) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL6893890 0.75 TTR (0.50) TTRLTA4HNR1H2BAXTSHR
SCHEMBL2210191 0.74 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL2943595 0.74 CYP1A2 (0.56) CYP1A2CYP3A4CYP2C9CYP2C19TTR
SCHEMBL2093898 0.74 LTA4H (0.55) TTRMAOBLTA4HNR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110311871-A1 NEGATIVE ELECTRODE FOR LITHIUM SECONDARY BATTERIES AND LITHIUM SECONDARY BATTERY SANYO ELECTRIC CO., LTD. (JP) 2011-12-22 US disclosed
US-8080319-B2 Thermosetting resin composition and use thereof Kippon Kayaku Kabushiki Kaisha (JP) 2011-12-20 US disclosed
US-20090286087-A1 Thermosetting Resin Composition and Use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-11-19 US disclosed
US-6686106-B2 POLYIMIDESILOXANE COPOLYMERS UBE INDUSTRIES, LTD. (JP) 2004-02-03 US disclosed
EP-1052252-B1 Diaminobenzene derivatives and dyeing preparations containing them WELLA AG (DE) 2003-08-06 EP disclosed
US-20020001763-A1 Photosensitive resin compositions, insulating films, and processes for formation of the films UBE INDUSTRIES, LTD. 2002-01-03 US disclosed
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed