Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456726 | 1.00 | FFAR1 (0.54) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2853680 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2853683 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL6716853 | 0.82 | FFAR1 (0.58) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2859750 | 0.79 | FFAR1 (0.85) | FFAR1FFAR4MMP2MMP12S1PR1 | |
| SCHEMBL4456719 | 0.79 | FFAR1 (0.50) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL1852799 | 0.78 | LMNA (0.57) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL2851095 | 0.77 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL5598328 | 0.77 | FFAR1 (0.59) | FFAR1FFAR4MMP2MMP12TNK2 | |
| SCHEMBL5598330 | 0.76 | FFAR1 (0.57) | FFAR1FFAR4MMP2MMP12TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |