Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.58 |
| ▸ | MGAM | O43451 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 7/20 | 0.52 |
| ▸ | SI | P14410 | 7/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 2/20 | 0.48 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457030 | 0.89 | DHODH (0.53) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8818948 | 0.87 | DHODH (0.55) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL230979 | 0.86 | DHODH (0.53) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL31027957 | 0.86 | DHODH (0.59) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL7146754 | 0.84 | DHODH (0.62) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL1170898 | 0.84 | DHODH (0.54) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL9346643 | 0.82 | GAA (0.54) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8816555 | 0.82 | DHODH (0.51) | MGAMGAASIMGAM2NPC1 | |
| SCHEMBL8891044 | 0.82 | MGAM (0.68) | MGAMGAASIMGAM2DHODH | |
| SCHEMBL8818524 | 0.82 | MGAM (0.68) | MGAMGAASIMGAM2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |