Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 6/20 | 0.68 |
| ▸ | SI | P14410 | 6/20 | 0.68 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.68 |
| ▸ | PARP1 | P09874 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 6/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457030 | 0.89 | DHODH (0.53) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL8818574 | 0.87 | GAA (0.64) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL230979 | 0.86 | DHODH (0.53) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL31027957 | 0.86 | DHODH (0.59) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL7146754 | 0.84 | DHODH (0.62) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL1170898 | 0.84 | DHODH (0.54) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL9346643 | 0.82 | GAA (0.54) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL8818524 | 0.82 | MGAM (0.68) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL8816555 | 0.82 | DHODH (0.51) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL8817536 | 0.82 | NR1I3 (0.58) | MGAMGAASIMGAM2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |