Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.33 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 5/20 | 0.32 |
| ▸ | F10 | P00742 | 5/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855107 | 0.96 | PTPN11 (0.36) | SLC6A4ALDH1A1LTB4R2HTR5AHTR1A | |
| SCHEMBL2861742 | 0.94 | SLC6A4 (0.37) | SLC6A4ALDH1A1LTB4R2HTR5AHTR1A | |
| SCHEMBL13711758 | 0.93 | SLC6A4 (0.41) | SLC6A4ALDH1A1LTB4R2HTR5AHTR1A | |
| SCHEMBL2854916 | 0.92 | CNR2 (0.36) | SLC6A4ALDH1A1LTB4R2HTR5AF2 | |
| SCHEMBL2853035 | 0.92 | GAA (0.37) | LTB4R2HTR5AACACBF2F10 | |
| SCHEMBL2857283 | 0.91 | PTGES (0.39) | SLC6A4ALDH1A1HTR5AACACBF2 | |
| SCHEMBL2853674 | 0.91 | LTB4R2 (0.37) | ALDH1A1LTB4R2F2F10PTGDR2 | |
| SCHEMBL2858908 | 0.90 | PTPN11 (0.36) | SLC6A4ALDH1A1LTB4R2HTR5AHTR1A | |
| SCHEMBL2861740 | 0.90 | SLC6A4 (0.34) | SLC6A4ALDH1A1LTB4R2HTR5AHTR1A | |
| SCHEMBL13711662 | 0.89 | SLC6A4 (0.41) | SLC6A4LTB4R2HTR5AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7589232-B2 | Alkynyl aryl carboxamides | LABORATORIES SERONO S.A. (CH) | 2009-09-15 | — | — | US | disclosed |
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
| US-20070105913-A1 | Alkynyl aryl carboxamides | APPLIED RESEARCH SYSTEMS ARS HOLDINGS N.V. (NL) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105913-A1 | Alkynyl aryl carboxamides | ECHS1, IRS1, HCCS | SLC6A4 3541/4885ALDH1A1 1454/4885LTB4R2 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.