SCHEMBL4457086

SCHEMBL4457086

CC(c1cc(Cl)c(O)c(Cl)c1)(c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 7/20 0.50
TSHR P16473 6/20 0.50
CYP3A4 P08684 4/20 0.50
RECQL P46063 4/20 0.50
TTR P02766 3/20 0.50
ALDH1A1 P00352 3/20 0.50
THRB P10828 3/20 0.46
HIF1A Q16665 5/20 0.44
ALOX15 P16050 4/20 0.44
ALOX12 P18054 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
CYP2C19 P33261 3/20 0.44
CYP2C9 P11712 2/20 0.44
CYP1A2 P05177 2/20 0.44
HPGD P15428 5/20 0.40
MAPK1 P28482 3/20 0.40
ACLY P53396 1/20 0.40
CASP1 P29466 3/20 0.38
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717889 0.87 ESR1 (0.55) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL9354191 0.85 ESR1 (0.45) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL6321695 0.84 GABRA1 (0.52) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL19109 0.84 HSD17B10 (0.52) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL29065613 0.82 GABRA1 (0.50) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL11702887 0.82 HSD17B10 (0.48) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL11566429 0.78 ESR1 (0.52) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL11698337 0.77 HSD17B10 (0.42) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL13038931 0.77 HSD17B10 (0.45) HSD17B10TSHRCYP3A4RECQLTTR
SCHEMBL7943477 0.77 TSHR (0.42) HSD17B10TSHRCYP3A4RECQLTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646613-B1 A branched polycarbonate and a process for producing the same IDEMITSU PETROCHEMICAL CO (JP) 2002-02-27 EP claimed
EP-0496258-B1 Polymer composition containing a branched polycarbonate IDEMITSU PETROCHEMICAL CO (JP) 2001-06-20 EP claimed
US-5473046-A Interfacial polymerization; heat resistance, corrosion resistance IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-12-05 US claimed
EP-0646613-A2 A branched polycarbonate and a process for producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1995-04-05 EP claimed
US-5243018-A Melt properties suitable for blow molding; appliances, business automation equipment, construction materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-09-07 US claimed
EP-0496258-A2 Polymer composition containing a branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
US-12398266-B2 Polycarbonate resin composition IDEMITSU KOSAN CO., LTD. (JP) 2025-08-26 US disclosed
US-12297349-B2 Transparent resin composition and transparent resin molded article Sony Group Corporation (JP) 2025-05-13 US disclosed
US-12024629-B2 Polycarbonate-based resin, production method therefor, and polycarbonate-based resin composition IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-20240199849-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES IDEMITSU KOSAN CO.,LTD. (JP) 2024-06-20 US disclosed
US-20240150574-A1 POLYCARBONATE RESIN COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
EP-4321555-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES Idemitsu Kosan Co.,Ltd. (JP) 2024-02-14 EP disclosed
EP-3336145-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2023-11-01 EP disclosed
US-5283314-A Polymerizing an oligomer of a dihydric phenol and a branching agent with a dihydric alcohol and a monohydric phenol with stirring IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-02-01 US disclosed
EP-0577849-A1 POLYCARBONATE AND PRODUCTION THEREOF DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1994-01-12 EP disclosed
US-5243018-A Melt properties suitable for blow molding; appliances, business automation equipment, construction materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-09-07 US disclosed
EP-0496257-A2 Polymer composition comprising a branched polycarbonate and a polyester IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-07-29 EP disclosed
EP-0496258-A2 Polymer composition containing a branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-07-29 EP disclosed
US-5104964-A Blow molding IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-04-14 US disclosed
EP-0411433-A2 Branched polycarbonate and process for production thereof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-02-06 EP disclosed