SCHEMBL9717889

SCHEMBL9717889

CC(c1ccccc1)(c1cc(Cl)c(O)c(Cl)c1)c1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.55
ESR2 Q92731 3/20 0.55
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 2/20 0.41
TTR P02766 3/20 0.39
HSD17B10 Q99714 2/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
AKR1C2 P52895 2/20 0.38
AKR1C1 Q04828 2/20 0.38
CYP19A1 P11511 2/20 0.38
ALOX15 P16050 2/20 0.38
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
THRB P10828 1/20 0.37
DHODH Q02127 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4457086 0.87 HSD17B10 (0.50) ESR1ESR2ALDH1A1CYP3A4TTR
SCHEMBL9354191 0.82 ESR1 (0.45) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL30829413 0.81 ESR2 (0.68) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL2030501 0.81 ESR2 (0.68) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL23861357 0.79 ESR1 (0.60) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL2004560 0.79 ESR1 (0.66) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL10837635 0.78 ESR1 (0.53) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL2858798 0.76 ESR1 (0.55) ESR1ESR2ALDH1A1CYP3A4TSHR
SCHEMBL9682952 0.76 ALDH1A1 (0.57) ESR1ESR2ALDH1A1CYP3A4TTR
SCHEMBL23059478 0.75 ESR1 (0.87) ESR1ESR2ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500131-A2 Polycarbonate resin solution for film formation by casting MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-08-26 EP disclosed
US-4866155-A HEAT, RADIATION RESISTANCE; TRANSPARENCY HOECHST CELANESE CORPORATION (US) 1989-09-12 US disclosed
EP-0323561-A2 Polyesters of bis (2-(4-hydroxyphenyl) hexafluoroisopropyl)- diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-07-12 EP disclosed
US-4444960-A POLYESTER, POLYSULFONATE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-04-24 US disclosed
US-4284549-A COMPRISING A POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A BISPHENOL AN POLYPHENYLENE SULFIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-08-18 US disclosed
US-4256625-A PERFLUOROALKENYLOXY, N-PHOSPHATOALKYL-SULFAMOYL-BENZENE SURFACTANT HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-03-17 US disclosed
US-4251429-A COMPRISING POLYPHENYLENE SULFIDE AND AN AROMATIC POLYESTER HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-02-17 US disclosed
US-4211687-A AROMATIC POLYESTER, POLYPHENYLENE SULFIDE, HALO DIELS-ADER ADDUCT HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-08 US disclosed
US-4187259-A Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-02-05 US disclosed
EP-0007171-A1 Polymer compositions, molded articles and films with improved hydrolytic stability HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-01-23 EP disclosed
US-4137278-A TRANSESTERIFICATION CATALYST HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-01-30 US disclosed
US-4126602-A THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-11-21 US disclosed
US-4079034-A AROMATIC POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A HALOGENATED BISPHENOL HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-03-14 US disclosed