Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27219492 | 0.83 | HTR6 (0.50) | HTR6ALDH1A1L3MBTL1POLBPPARG | |
| SCHEMBL17747381 | 0.80 | HTR6 (0.49) | HTR6MAPTHTTL3MBTL1POLB | |
| SCHEMBL17747382 | 0.80 | HTR6 (0.49) | HTR6MAPTHTTL3MBTL1POLB | |
| SCHEMBL1894102 | 0.80 | HTR6 (0.61) | HTR6LMNAMAPTALDH1A1HTT | |
| SCHEMBL28623603 | 0.79 | HTR6 (0.44) | HTR6L3MBTL1POLBPPARGRAPGEF4 | |
| SCHEMBL10004175 | 0.79 | HTR6 (0.53) | HTR6APOBEC3AAPOBEC3G | |
| SCHEMBL31154316 | 0.75 | HTR6 (0.45) | HTR6L3MBTL1POLBPPARGRAPGEF4 | |
| SCHEMBL31668439 | 0.75 | L3MBTL1 (0.43) | HTR6LMNASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4446722 | 0.75 | HTR6 (0.59) | HTR6LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL17049298 | 0.75 | HTR6 (0.56) | HTR6LMNAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145357-A1 | IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |