Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.36 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876484 | 0.84 | ALDH1A1 (0.45) | TSHRHSD17B10KDM4EALDH1A1TDP1 | |
| SCHEMBL11062721 | 0.80 | HSD17B10 (0.45) | TSHRHSD17B10CA2KDM4EALDH1A1 | |
| SCHEMBL1022506 | 0.78 | ALDH1A1 (0.54) | TSHRHSD17B10CA2KDM4EALDH1A1 | |
| SCHEMBL16555940 | 0.78 | ALDH1A1 (0.43) | TSHRKDM4EALDH1A1TDP1MAPK1 | |
| SCHEMBL10804924 | 0.77 | HSD17B10 (0.44) | TSHRHSD17B10KDM4EALDH1A1TDP1 | |
| SCHEMBL536362 | 0.76 | HSD17B10 (0.54) | TSHRHSD17B10CA2ALDH1A1TDP1 | |
| SCHEMBL3628365 | 0.76 | ALDH1A1 (0.52) | TSHRHSD17B10CA2KDM4EALDH1A1 | |
| SCHEMBL10941731 | 0.76 | ALDH1A1 (0.42) | TSHRKDM4EALDH1A1TDP1MAPK1 | |
| SCHEMBL30599573 | 0.76 | ALDH1A1 (0.52) | TSHRHSD17B10CA2KDM4EALDH1A1 | |
| SCHEMBL9798590 | 0.76 | SMN1; SMN2 (0.47) | TSHRKDM4EALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
| EP-3700340-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | Dow Agrosciences LLC (US) | 2020-09-02 | — | — | EP | disclosed |
| CN-111278283-A | Pyridine and pyrimidine formate herbicides and methods of use thereof | 美国陶氏益农公司 | 2020-06-12 | — | — | CN | disclosed |
| EP-2955178-A1 | CONDENSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-12-16 | — | — | EP | disclosed |
| US-7524882-B2 | PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders | MERCK & CO., INC. (US) | 2009-04-28 | — | — | US | disclosed |
| EP-1539136-B1 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK & CO INC (US) | 2008-07-09 | — | — | EP | disclosed |
| EP-1539136-A4 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK & CO INC (US) | 2006-10-18 | — | — | EP | disclosed |
| US-20050228044-A1 | Ppar alpha selective compounds for the treatment of dyslipidemia and other lipid disorders | MERCK SHARP & DOHME CORP. | 2005-10-13 | — | — | US | disclosed |
| EP-1539136-A2 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | Merck & Co., Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004010936-A2 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK & CO., INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| US-4700006-A | FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-10-13 | — | — | US | disclosed |
| US-4609669-A | AGRICULTURE, HORTICULTURE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-09-02 | — | — | US | disclosed |
| EP-0104473-B1 | PHENOXYALKANOIC-ACID COMPOUNDS FOR REGULATING PLANT GROWTH | BASF Aktiengesellschaft (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4523034-A | Herbicidal diphenyl ethers, their preparation and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | disclosed |
| EP-0104473-A1 | Phenoxyalkanoic-acid compounds for regulating plant growth | BASF Aktiengesellschaft (DE) | 1984-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | TSHR 1867/4885HSD17B10 1881/4885CA2 1070/4885 |
| US-20050228044-A1 | Ppar alpha selective compounds for the treatment of dyslipidemia and other lipid disorders | PPARD, PPARA, PPARG | TSHR 1138/4885HSD17B10 72/4885CA2 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.