Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | BLVRB | P30043 | 1/20 | 0.59 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877752 | 0.91 | XDH (0.51) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29460288 | 0.89 | XDH (0.74) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL14240896 | 0.87 | XDH (0.78) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30253977 | 0.83 | XDH (0.76) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL27895928 | 0.83 | XDH (0.76) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL12127713 | 0.82 | XDH (0.46) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL454804 | 0.81 | XDH (0.75) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30804875 | 0.80 | XDH (0.73) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29183566 | 0.80 | XDH (0.73) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL19523341 | 0.79 | XDH (0.79) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992361-B1 | Remedy or preventive for digestive ulcer | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-1932832-B1 | TRIARYLCARBOXYLIC ACID DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2010-12-01 | — | — | EP | disclosed |
| EP-1992361-A1 | REMEDY OR PREVENTIVE FOR DIGESTIVE ULCER | Astellas Pharma Inc. (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1932832-A1 | TRIARYLCARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-06-18 | — | — | EP | disclosed |