Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | BLVRB | P30043 | 1/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457485 | 0.91 | XDH (0.59) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL4448051 | 0.83 | XDH (0.44) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL29460288 | 0.82 | XDH (0.74) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL12127713 | 0.82 | XDH (0.46) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL14037590 | 0.81 | XDH (0.46) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL14240896 | 0.78 | XDH (0.78) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL4451557 | 0.77 | ALDH1A1 (0.49) | XDHALDH1A1HPGD | |
| SCHEMBL29183565 | 0.77 | XDH (0.59) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30804881 | 0.77 | XDH (0.59) | XDHABCC4ABCB11PGRCHRM1 | |
| SCHEMBL30253977 | 0.76 | XDH (0.76) | XDHABCC4ABCB11PGRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426453-B2 | Treatment of a stomach or small intestine ulcer with 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid | ASTELLAS PHARMA INC. (JP) | 2013-04-23 | — | — | US | disclosed |