Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 14/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451188 | 0.89 | RAB9A (0.61) | RAB9AMAPTNPSR1EPHX1NPC1 | |
| SCHEMBL6687894 | 0.84 | EPHX1 (0.60) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2184501 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL16722248 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2184904 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2189540 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2185950 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2185689 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2185919 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE | |
| SCHEMBL2185439 | 0.82 | EPHX1 (0.63) | RAB9AMAPTNPSR1EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635742-B2 | Crosslinking polyurethanes | RHODIA CHIMIE (FR) | 2009-12-22 | — | — | US | disclosed |
| US-20040073046-A1 | Modified isocyanates | RHODIA CHIMIE (FR) | 2004-04-15 | — | — | US | disclosed |
| US-20030050424-A1 | Modified isocyanates | RHODIA CHIMIE (FR) | 2003-03-13 | — | — | US | disclosed |