Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701109 | 0.91 | PRKCI (0.52) | PRKCICYP2A6FAAHPIK3CBCHRNA7 | |
| SCHEMBL3133961 | 0.91 | PRKCI (0.52) | PRKCICYP2A6FAAHPIK3CBCHRNA7 | |
| SCHEMBL14571688 | 0.85 | QDPR (0.53) | PRKCICYP2A6FAAHCHRNA7HRH3 | |
| SCHEMBL23442948 | 0.84 | SLC6A2 (0.49) | PRKCICYP2A6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29891558 | 0.84 | SLC6A2 (0.49) | PRKCICYP2A6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25167084 | 0.78 | QDPR (0.45) | PRKCICYP2A6FAAHCHRNA7HRH3 | |
| SCHEMBL17683262 | 0.77 | HTR1D (0.49) | PRKCICYP2A6PIK3CBCHRNA7SLC6A4 | |
| SCHEMBL27527522 | 0.77 | HTR1D (0.41) | BACE1TRIM24HRH3HTR1D | |
| SCHEMBL12791617 | 0.74 | BRPF1 (0.53) | BACE1TRIM24ABL1HRH3SLC6A4 | |
| SCHEMBL13477895 | 0.74 | KMT2A (0.44) | BACE1TRIM24SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145357-A1 | IN 1-POSITION DURCH EINEN RING SUBSTITUIERTE BENZO [1, 4] DIAZEPINE ZUR VERWENDUNGS ALS ANTIDEPRESSIVA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |