SCHEMBL4458013

SCHEMBL4458013

CCOPc1cccc(CC)c1CC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.38
GABRB2 P47870 4/20 0.38
TAAR1 Q96RJ0 2/20 0.37
HTR1A P08908 1/20 0.37
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PDK2 Q15119 1/20 0.32
NLRP3 Q96P20 1/20 0.31
TP53 P04637 1/20 0.31
KCNH2 Q12809 2/20 0.31
SCN5A Q14524 2/20 0.31
DAO P14920 1/20 0.30
CACNA1C Q13936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4450212 0.86 GABRA1 (0.35) GABRA1GABRB2TAAR1HTR1AMAPT
SCHEMBL4455680 0.83 GABRA1 (0.39) GABRA1GABRB2TAAR1HTR1AMAPT
SCHEMBL4462062 0.83 TDP1 (0.36) GABRA1GABRB2TAAR1HTR1AMAPT
SCHEMBL11230429 0.82 MAPT (0.40) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL4452192 0.80 TAAR1 (0.36) GABRA1GABRB2TAAR1HTR1AMAPT
SCHEMBL4460825 0.79 ELANE (0.32)
SCHEMBL11630937 0.78 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1AMAPT
SCHEMBL4454772 0.77 GABRA1 (0.34) GABRA1GABRB2TAAR1HTR1AMAPT
SCHEMBL4452258 0.76 PTGS2 (0.36)
SCHEMBL4450169 0.74 TAAR1 (0.34) GABRA1GABRB2TAAR1HTR1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed