SCHEMBL4458092

SCHEMBL4458092

c1ccc(P(OC2CC2)OC2CC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HRH1 P35367 1/20 0.33
SLC6A4 P31645 2/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454309 0.91 CYP3A4 (0.35) CYP3A4TDP1HRH1
SCHEMBL2940772 0.89 FABP7 (0.36) CYP3A4TDP1
SCHEMBL4457992 0.81 CYP3A4 (0.38) CYP3A4TDP1HRH1SLC6A4SLC6A2
SCHEMBL4451111 0.73 CYP3A4 (0.35) CYP3A4TDP1HRH1
SCHEMBL1726166 0.71 FABP7 (0.36) CYP3A4TDP1
SCHEMBL4459830 0.70 TSHR (0.35) SLC6A4SLC6A2SLC6A3
SCHEMBL4462491 0.68 HRH1 (0.39) TDP1HRH1SLC6A4SLC6A2SLC6A3
SCHEMBL11029955 0.64 CYP3A4 (0.35) CYP3A4TDP1
SCHEMBL196040 0.64 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2
SCHEMBL911476 0.63 CYP3A4 (0.39) CYP3A4TDP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed