SCHEMBL4451111

SCHEMBL4451111

c1ccc(P(OC2CCC2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
OPRM1 P35372 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32
HRH1 P35367 1/20 0.31
FABP7 O15540 1/20 0.30
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1726166 0.94 FABP7 (0.36) CYP3A4TDP1FABP7FABP5
SCHEMBL11027299 0.92 CYP3A4 (0.32) CYP3A4TDP1OPRM1OPRD1OPRK1
SCHEMBL4457992 0.91 CYP3A4 (0.38) CYP3A4TDP1HRH1
SCHEMBL11029955 0.83 CYP3A4 (0.35) CYP3A4TDP1OPRM1OPRD1OPRK1
SCHEMBL4454309 0.83 CYP3A4 (0.35) CYP3A4TDP1HRH1FABP7FABP5
SCHEMBL6860443 0.79 OPRM1 (0.33) OPRM1OPRD1OPRK1
SCHEMBL5168607 0.78 CYP3A4 (0.35) CYP3A4TDP1OPRM1OPRD1OPRK1
SCHEMBL2912861 0.78 CYP3A4 (0.35) CYP3A4TDP1OPRM1OPRD1OPRK1
SCHEMBL2940772 0.77 FABP7 (0.36) CYP3A4TDP1FABP7FABP5
SCHEMBL6860925 0.74 TRPA1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed