SCHEMBL4457992

SCHEMBL4457992

c1ccc(P(OC2CC2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HRH1 P35367 1/20 0.33
SLC6A4 P31645 2/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A3 Q01959 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451111 0.91 CYP3A4 (0.35) CYP3A4TDP1HRH1
SCHEMBL1726166 0.89 FABP7 (0.36) CYP3A4TDP1KDM4E
SCHEMBL11027299 0.83 CYP3A4 (0.32) CYP3A4TDP1SLC6A4SLC6A2SLC6A3
SCHEMBL4458092 0.81 CYP3A4 (0.38) CYP3A4TDP1HRH1SLC6A4SLC6A2
SCHEMBL11029955 0.77 CYP3A4 (0.35) CYP3A4TDP1
SCHEMBL2912861 0.77 CYP3A4 (0.35) CYP3A4TDP1GAA
SCHEMBL5168607 0.77 CYP3A4 (0.35) CYP3A4TDP1GAA
SCHEMBL6854137 0.74 LMNA (0.33) CYP3A4TDP1
SCHEMBL4454309 0.73 CYP3A4 (0.35) CYP3A4TDP1HRH1
SCHEMBL6860808 0.73 CYP3A4 (0.35) CYP3A4TDP1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed