Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552930 | 0.83 | — | — | |
| SCHEMBL2154182 | 0.81 | CAPN1 (0.46) | CAPN1 | |
| SCHEMBL1039137 | 0.80 | TSHR (0.40) | — | |
| Hydrochloric Acid SCHEMBL1039136 | 0.79 | TSHR (0.39) | — | |
| SCHEMBL8448307 | 0.77 | CYP4F2 (0.45) | — | |
| SCHEMBL28715109 | 0.77 | LMNA (0.38) | — | |
| SCHEMBL216266 | 0.75 | FFAR1 (0.39) | — | |
| SCHEMBL6443420 | 0.75 | — | — | |
| SCHEMBL9642033 | 0.75 | TSHR (0.41) | — | |
| SCHEMBL14306754 | 0.75 | IAPP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293900-B2 | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators | MERCK SHARP & DOHME CORP (US) | 2012-10-23 | — | — | US | disclosed |
| US-20090170863-A1 | Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators | MERCK & CO., INC. (US) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170863-A1 | Acylated Spiropiperidine Derivatives as Melanocortin-4 Receptor Modulators | MC4R, MC5R, MC3R | CAPN1 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.