SCHEMBL216266

SCHEMBL216266

O=C(O)CCc1c[nH]cn1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.39
KEAP1 Q14145 1/20 0.38
P4HTM Q9NXG6 1/20 0.37
NPSR1 Q6W5P4 1/20 0.35
TBXAS1 P24557 3/20 0.35
CHRM1 P11229 1/20 0.34
NR1H4 Q96RI1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1311654 0.98 FFAR1 (0.38) FFAR1KEAP1P4HTMNPSR1TBXAS1
Hydrochloric Acid SCHEMBL6625511 0.98 FFAR1 (0.38) FFAR1KEAP1P4HTMNPSR1TBXAS1
SCHEMBL18906027 0.89 SMN1; SMN2 (0.41) TBXAS1
SCHEMBL291231 0.87 TBXAS1 (0.46) TBXAS1
Hydrochloric Acid SCHEMBL11161336 0.87 TBXAS1 (0.41) TBXAS1
Histamine SCHEMBL5321413 0.85 LMNA (0.33) P4HTMNPSR1TBXAS1
SCHEMBL2896033 0.85 TBXAS1 (0.49) TBXAS1
SCHEMBL26589771 0.85 TBXAS1 (0.49) TBXAS1
Histamine SCHEMBL1680140 0.85 LMNA (0.33) P4HTMNPSR1TBXAS1
SCHEMBL6443420 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689898-B1 LONG-ACTING CONJUGATE OF GLUCAGON-LIKE PEPTIDE-2 (GLP-2) DERIVATIVE HANMI PHARMACEUTICAL CO LTD (KR) 2026-04-29 EP claimed
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP claimed
US-20250311759-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-10-09 US claimed
WO-2025069009-A1 ROCK2 INHIBITORS IN THE TREATMENT OF OBESITY GRAVITON BIOSCIENCE BV (NL) 2025-04-03 WO claimed
CN-119325387-A Combination therapy of GLP-2 with insulinotropic peptide, TNFa inhibitor or both for preventing or treating intestinal diseases 韩美药品株式会社 2025-01-17 CN claimed
WO-2024245421-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-12-05 WO claimed
CN-118401257-A Methods for producing antibody peptide conjugates 美国安进公司 2024-07-26 CN claimed
CN-110831969-B Methods of treating or ameliorating metabolic disorders using a combination of a Gastric Inhibitory Peptide Receptor (GIPR) binding protein and a GLP-1 agonist 安进公司 2024-06-21 CN claimed
EP-3891176-B1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2024-06-05 EP claimed
CN-118079021-A Treatment or amelioration of metabolic disorders using GLP-1 receptor agonists coupled to Gastric Inhibitory Peptide Receptor (GIPR) antagonists 美国安进公司 2024-05-28 CN claimed
EP-3118211-A1 AMIDE COMPOUNDS AND METHODS FOR THE PRODUCTION AND USE THEREOF Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) 2017-01-18 EP claimed
US-20090011124-A1 Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(1-methylimidazole)2(2-ethylhexanoate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes HSIEH BING 2009-01-08 US claimed
EP-1778778-A2 ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS King Industries, Inc. (US) 2007-05-02 EP claimed
US-20060247341-A1 Complexes of zinc with substituted amidines and guanidines and aliphatic carboxylates, e.g., Zn(1-methylimidazole)2(acetate)2 and Zn(tetramethylguanidine)2(formate)2; useful as catalysts for deblocking blocked isocyanates and in the production of urethanes and polyurethanes KING INDUSTRIES, INC. 2006-11-02 US claimed
WO-2006022899-A2 ORGANOMETALLIC COMPOSITIONS AND COATING COMPOSITIONS KING INDUSTRIES, INC. (US) 2006-03-02 WO claimed
US-20060036007-A1 Organometallic compositions and coating compositions KING INDUSTRIES, INC. (US) 2006-02-16 US claimed
CN-1338456-A Benzodiazepine compound containing imidazole propionamido and preparation method and application thereof INST OF MEDICAL MATERIALS CHIN (CN) 2002-03-06 CN claimed
EP-0597088-B1 NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS INST NAT SANTE RECH MED (FR) 2000-12-06 EP claimed
US-5708171-A HISTAMINE H3-RECEPTOR ANTAGONIST INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1998-01-13 US claimed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN claimed