Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | ILK | Q13418 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | QPCT | Q16769 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17234165 | 0.91 | POLB (0.68) | POLBNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL30920002 | 0.91 | POLB (0.68) | POLBNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL2790542 | 0.84 | RAB9A (0.75) | POLBNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL6640386 | 0.82 | POLB (0.62) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11074021 | 0.82 | NPC1 (0.63) | POLBNPC1RAB9AILKSMN1; SMN2 | |
| SCHEMBL11887784 | 0.82 | POLB (0.84) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1822190 | 0.81 | NPC1 (0.58) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1981971 | 0.81 | NPC1 (0.62) | POLBNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL22039978 | 0.81 | NPC1 (0.61) | NPC1RAB9AILKSMN1; SMN2MEN1 | |
| SCHEMBL3239389 | 0.81 | POLB (0.82) | POLBNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| US-8273775-B2 | Non-steroidal brassinosteroid mimetic | VIB VZW (BE) | 2012-09-25 | — | — | US | disclosed |
| EP-2086322-B1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2010-12-01 | — | — | EP | disclosed |
| US-20100152253-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | VIB VZW (BE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152253-A1 | NON-STEROIDAL BRASSINOSTEROID MIMETIC | BRI3BP, BRD1, NR1I2 | POLB 4205/4885NPC1 1491/4885RAB9A 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.