Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103217 | 0.95 | PARP1 (0.46) | PARP1DPP4MAP4K4USP2SMN1; SMN2 | |
| SCHEMBL102292 | 0.95 | PARP1 (0.46) | PARP1DPP4MAP4K4USP2SMN1; SMN2 | |
| SCHEMBL102293 | 0.95 | PARP1 (0.46) | PARP1DPP4MAP4K4USP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL377440 | 0.94 | PARP1 (0.45) | PARP1DPP4MAP4K4USP2SMN1; SMN2 | |
| Potassium SCHEMBL30616188 | 0.94 | PARP1 (0.45) | PARP1DPP4MAP4K4USP2SMN1; SMN2 | |
| Methane SCHEMBL28975622 | 0.94 | PARP1 (0.45) | PARP1DPP4MAP4K4USP2SMN1; SMN2 | |
| SCHEMBL25212939 | 0.86 | PARP1 (0.41) | PARP1USP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL25416105 | 0.86 | PARP1 (0.41) | PARP1USP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL25268281 | 0.86 | PARP1 (0.41) | PARP1USP2SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL22604987 | 0.84 | HPGD (0.41) | PARP1SMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | DHPS, AQP4, OGFOD1 | PARP1 1083/4885DPP4 2178/4885MAP4K4 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.