SCHEMBL4458909

SCHEMBL4458909

Cc1c(O)ccc2c1C1(CC2(C)C)CC(C)(C)c2ccc(O)c(C)c21

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.49
TP53 P04637 1/20 0.49
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
TRPA1 O75762 1/20 0.34
ATM Q13315 1/20 0.34
ACHE P22303 1/20 0.33
CNR2 P34972 1/20 0.33
MEN1 O00255 1/20 0.33
TNNI3 P19429 1/20 0.33
TNNT2 P45379 1/20 0.33
TNNC1 P63316 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404169 1.00 CYP1A2 (0.49) CYP1A2TP53ESR1ESR2TRPA1
SCHEMBL9326775 0.82 CYP1A2 (0.46) CYP1A2TP53TRPA1MEN1TNNI3
SCHEMBL8012808 0.80 TP53 (0.53) CYP1A2TP53MEN1TNNI3TNNT2
SCHEMBL4462287 0.79 TP53 (0.43) CYP1A2TP53MEN1TNNI3TNNT2
SCHEMBL23450027 0.79 TP53 (0.43) CYP1A2TP53MEN1TNNI3TNNT2
SCHEMBL4474118 0.77 TP53 (0.41) CYP1A2TP53ESR1ESR2MEN1
SCHEMBL4455636 0.76 TP53 (0.39) CYP1A2TP53TRPA1ATMACHE
SCHEMBL29740745 0.76 TP53 (0.39) CYP1A2TP53TRPA1ATMACHE
SCHEMBL10001261 0.76 ACHE (0.35) ACHE
SCHEMBL21565070 0.75 TP53 (0.44) CYP1A2TP53MEN1TNNI3TNNT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3214109-B1 POLYCARBONATE RESIN, MOLDED ARTICLE AND OPTICAL FILM MITSUBISHI CHEM CORP (JP) 2024-08-21 EP disclosed
US-11285710-B2 Multilayer body TEIJIN LIMITED (JP) 2022-03-29 US disclosed
US-20200316928-A1 MULTILAYER BODY TEIJIN LIMITED (JP) 2020-10-08 US disclosed
EP-3575340-B1 POLYCARBONATE COPOLYMER TEIJIN LTD (JP) 2020-07-15 EP disclosed
US-10081707-B2 Polycarbonate resin, molded article, and optical film MITSUBISHI CHEMICAL CORPORATION (JP) 2018-09-25 US disclosed
EP-3214109-A1 POLYCARBONATE RESIN, MOLDED ARTICLE AND OPTICAL FILM Mitsubishi Chemical Corporation (JP) 2017-09-06 EP disclosed
US-20170204220-A1 POLYCARBONATE RESIN, MOLDED ARTICLE, AND OPTICAL FILM MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed