SCHEMBL4458944

SCHEMBL4458944

C=CCNC(=O)OCCC

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.47
FAAH O00519 1/20 0.46
CHRNB2 P17787 2/20 0.41
CHRNB4 P30926 2/20 0.41
CHRNA3 P32297 2/20 0.41
CHRNA4 P43681 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 1/20 0.41
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486852 0.89 ACHE (0.55) ACHEFAAHTSHR
SCHEMBL23111386 0.87 TSHR (0.46) ACHEFAAHSMN1; SMN2TSHRMAPT
SCHEMBL29939 0.87 ACHE (0.58) ACHEFAAH
SCHEMBL11338236 0.85 ACHE (0.61) ACHEFAAHTSHR
SCHEMBL20839538 0.85 ACHE (0.61) ACHEFAAHTSHR
SCHEMBL87647 0.83
SCHEMBL21570876 0.82 TSHR (0.48) ACHEFAAHCHRNB2CHRNB4CHRNA3
SCHEMBL14959695 0.82 ACHE (0.48) ACHESMN1; SMN2ALDH1A1MAPK1
SCHEMBL13836286 0.82 ACHE (0.50) ACHEFAAHSMN1; SMN2TSHRMAPT
Methyl Alcohol SCHEMBL11130161 0.82 ALDH1A1 (0.46) FAAHSMN1; SMN2TSHRMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234521-A Water-based lubricating liquid for stamping stainless steel plates and preparation method thereof 广州科卢斯流体科技有限公司 2021-08-10 CN claimed
CN-117529340-A Improved compositions for delivery of mRNA 翻译生物公司 2024-02-06 CN disclosed
EP-3743270-B1 CAST-MOLDING PROCESS FOR PRODUCING UV-ABSORBING CONTACT LENSES ALCON INC (CH) 2022-06-08 EP disclosed
EP-1601723-B1 DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHNSON & JOHNSON VISION CARE (US) 2018-10-31 EP disclosed
EP-3370107-A1 METHODS AND APPARATUS FOR ELECTROACTIVE VARIABLE APERTURE LENSES Johnson & Johnson Vision Care Inc. (US) 2018-09-05 EP disclosed
EP-2635927-B1 SILICONE HYDROGEL REACTIVE MIXTURES COMPRISING BORATES JOHNSON & JOHNSON VISION CARE (US) 2014-11-26 EP disclosed
EP-2061818-A2 HYDROPHILIC MACROMONOMERS HAVING ALPHA, BETA -CONJUGATED CARBOXYLIC TERMINAL GROUP AND MEDICAL DEVICES INCORPORATING SAME Bausch & Lomb Incorporated (US) 2009-05-27 EP disclosed
EP-2035050-A2 MODIFICATION OF SURFACES OF POLYMERIC ARTICLES BY MICHAEL ADDITION REACTION Bausch & Lomb Incorporated (US) 2009-03-18 EP disclosed
US-7381517-B2 Curable composition and image forming material containing the same FUJIFILM CORPORATION (JP) 2008-06-03 US disclosed
US-7381517-B2 Curable composition and image forming material containing the same FUJIFILM CORPORATION (JP) 2008-06-03 US disclosed
WO-2008005753-A2 HYDROPHILIC MACROMONOMERS HAVING α, β -CONJUGATED CARBOXYLIC TERMINAL GROUP AND MEDICAL DEVICES INCORPORATING SAME BAUSCH & LOMB INCORPORATED (US) 2008-01-10 WO disclosed
WO-2008005752-A2 MODIFICATION OF SURFACES OF POLYMERIC ARTICLES BY MICHAEL ADDITION REACTION BAUSCH & LOMB INCORPORATED (US) 2008-01-10 WO disclosed
US-20080003259-A1 Modification of surfaces of polymeric articles by Michael addition reaction BAUSCH & LOMB INCORPORATED 2008-01-03 US disclosed
EP-1601723-A4 DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHSON & JOHNSON VISION CARE I (US) 2007-06-20 EP disclosed
WO-2007047716-A2 SURFACE-MODIFIED MEDICAL DEVICES AND METHOD OF MAKING BAUSCH & LOMB INCORPORATED (US) 2007-04-26 WO disclosed
US-20070087113-A1 Surface-modified medical devices and method of making BAUSCH & LOMB INCORPORATED 2007-04-19 US disclosed
EP-1601723-A2 DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES J & J Vision Care, Inc. (US) 2005-12-07 EP disclosed
WO-2004081105-A2 DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JONHSON AND JOHNSON VISION CARE, INC. (US) 2004-09-23 WO disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4160846-A Method for controlling insects with tetrasubstituted organotin compounds UNIROYAL, INC. (US) 1979-07-10 US disclosed