Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113852 | 0.88 | IDO1 (0.59) | IDO1AGXTMPOKDM4ESMN1; SMN2 | |
| SCHEMBL26625794 | 0.88 | IDO1 (0.59) | IDO1AGXTMPOKDM4ESMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4243585 | 0.73 | IDO1 (0.44) | IDO1AGXTALDH1A1HTR2AHTR2C | |
| SCHEMBL1116576 | 0.73 | IDO1 (0.57) | IDO1AGXTMPOKDM4ESMN1; SMN2 | |
| SCHEMBL29431834 | 0.73 | IDO1 (0.57) | IDO1AGXTMPOKDM4ESMN1; SMN2 | |
| SCHEMBL12496555 | 0.72 | MAOB (0.48) | IDO1AGXTMPOLOXL2HTR2C | |
| SCHEMBL1398042 | 0.72 | MPO (0.48) | IDO1AGXTMPOKDM4ESMN1; SMN2 | |
| SCHEMBL28750348 | 0.72 | ADRA2B (0.45) | IDO1AGXTKDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2209462 | 0.71 | IDO1 (0.59) | IDO1AGXTMPOKDM4ESMN1; SMN2 | |
| SCHEMBL554229 | 0.71 | SLC6A2 (0.33) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819000-B1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2009-07-08 | — | — | EP | disclosed |