Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777297 | 0.94 | TSHR (0.55) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15751057 | 0.92 | LMNA (0.58) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15750966 | 0.90 | TSHR (0.60) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL7682936 | 0.90 | TSHR (0.60) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL3684650 | 0.90 | TSHR (0.60) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL7689391 | 0.90 | TSHR (0.60) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL225702 | 0.88 | TSHR (0.71) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL94565 | 0.88 | TSHR (0.71) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL15750869 | 0.86 | LMNA (0.58) | TSHRLMNASLC22A6NFKB1PMP22 | |
| SCHEMBL23046863 | 0.86 | TSHR (0.77) | TSHRLMNASLC22A6NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164650-A | Preparation and application of intelligent response type trisulfide bridged doxorubicin monomer prodrug | 沈阳药科大学 | 2023-12-05 | — | — | CN | claimed |
| CN-117700378-A | Four-sulfur bond bridged dimer prodrug, self-assembled nanoparticle thereof and application thereof | 沈阳药科大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-117164650-A | Preparation and application of intelligent response type trisulfide bridged doxorubicin monomer prodrug | 沈阳药科大学 | 2023-12-05 | — | — | CN | disclosed |
| EP-2738208-B1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEM (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9200145-B2 | Coupling agent for rubber/carbon black, and rubber composition containing same for use in tires | SHIKOKU CHEMICALS CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140155541-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEMICALS CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-2738208-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | Shikoku Chemicals Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-20090012233-A1 | Epoxy Resin Molding Material for Sealing and Electronic Component Device | HITACHI CHEMICAL CO., LTD. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-0552376-B1 | PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE | NIPPON CATALYTIC CHEM IND (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0552376-A1 | PRODUCTION OF POLYMER HYDROXYLATED AT BOTH TERMINALS, COMPOSITION CONTAINING SAID POLYMER AND ITS USE, AND POLYMER DERIVED FROM SAID COMPOSITION AND ITS USE | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |