SCHEMBL94565

SCHEMBL94565

O=C(O)CCCSSCCCC(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
LMNA P02545 5/20 0.59
SLC22A6 Q4U2R8 2/20 0.59
NFKB1 P19838 2/20 0.56
PMP22 Q01453 1/20 0.56
FOLH1 Q04609 2/20 0.54
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CAMK2A Q9UQM7 1/20 0.50
ALDH1A1 P00352 2/20 0.48
GABRR3 A8MPY1 1/20 0.48
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
HDAC3 O15379 1/20 0.48
GABBR2 O75899 1/20 0.48
CYP1A2 P05177 1/20 0.48
THRB P10828 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225702 1.00 TSHR (0.71) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL23046863 0.97 TSHR (0.77) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL20387044 0.92 TSHR (0.63) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL1163970 0.91 TSHR (0.67) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL6828156 0.88 TSHR (0.67) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL1163365 0.88 TSHR (0.67) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL1673083 0.88 TSHR (0.67) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL1163681 0.88 TSHR (0.67) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL931298 0.88 TSHR (0.67) TSHRLMNASLC22A6NFKB1PMP22
SCHEMBL4459033 0.88 TSHR (0.55) TSHRLMNASLC22A6NFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 953 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118001240-B Podophyllotoxin-9-fluorenylmethanol small molecule prodrug nanoparticle and preparation method and application thereof SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN claimed
US-20250361441-A1 ETCHING COMPOSITION, ETCHING METHOD, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING GATE-ALL-AROUND-TYPE TRANSISTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2025-11-27 US claimed
US-20250325513-A1 CABAZITAXEL PRODRUG ANTI-TUMOR PREPARATION UNIV SHENYANG PHARMACEUTICAL (CN) 2025-10-23 US claimed
US-12419551-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-09-23 US claimed
EP-4590782-A1 GAS-PHASE COMPOSITION FOR INHIBITING CORROSION EXPOSED TO CONDENSED WATER Arkema France (FR) 2025-07-30 EP claimed
CN-120039004-A Lightweight anti-tearing PVC (polyvinyl chloride) lamp box cloth 山东汇锋新材料有限公司 2025-05-27 CN claimed
WO-2025096734-A1 MICROCAPSULES FMC CORPORATION (US) 2025-05-08 WO claimed
WO-2025074986-A1 MODIFIED POLYCARBONATE, METHOD FOR PRODUCING MODIFIED POLYCARBONATE, AND RESIN COMPOSITION 株式会社カネカ 2025-04-10 WO claimed
EP-3965657-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-03-05 EP claimed
CN-119531139-A Wear-resistant and soil-release case fabric and processing method thereof 南通友途新材料科技有限公司 2025-02-28 CN claimed
EP-0675712-A1 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS HANDELMAN, Joseph H. (US) 1995-10-11 EP claimed
US-5411991-A Applying to human skin, beards, reaction with cysteine GILLETTE COMPANY, THE, A DELAWARE CORPORATION 1995-05-02 US claimed
EP-0635548-A1 Thermoplastic resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 1995-01-25 EP claimed
WO-1994014428-A1 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS HANDELMAN, JOSEPH, H. (US) 1994-07-07 WO claimed
EP-0497810-B1 TONE CONTROLLING COMPOUNDS KODAK LTD (GB) 1994-06-08 EP claimed
EP-0579089-A1 Polyether ester amide-sulfur vulcanized rubber compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-01-19 EP claimed
US-5239004-A A curied addition-condensation copolymer grafted by at least one dithiodiacid; odorless, stiffness, tensile strength THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-08-24 US claimed
EP-0549977-A1 Carboxyl-containing polyphenylene sulfide, process for producing the same, and resin composition containing the same MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-07-07 EP claimed
US-4377418-A Particulate filler, coated with material bonded thereto and containing a sulfur-containing group which releases sulfur as a curing agent for s-curable unsaturated polymers IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1983-03-22 US claimed
EP-0038620-A2 Particulate filler and polymer composition containing the filler IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-10-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419551-B2 Mediation of in vivo analyte signal degradation SLC2A1, TXN2, SLC2A8 TSHR 1204/4885LMNA 4443/4885SLC22A6 569/4885
US-20250325513-A1 CABAZITAXEL PRODRUG ANTI-TUMOR PREPARATION FASN, EBP, CTNNB1 TSHR 4608/4885LMNA 217/4885SLC22A6 1612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.