⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635146 | 0.78 | — | — | |
| SCHEMBL6841655 | 0.73 | — | — | |
| SCHEMBL508067 | 0.69 | — | — | |
| SCHEMBL3434919 | 0.68 | — | — | |
| SCHEMBL445607 | 0.67 | — | — | |
| SCHEMBL27649160 | 0.63 | — | — | |
| SCHEMBL365576 | 0.62 | — | — | |
| SCHEMBL9561396 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL1634746 | 0.61 | — | — | |
| SCHEMBL1173118 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601245-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | Biofilm IP, LLC (US) | 2013-06-12 | — | — | EP | claimed |
| US-20120064022-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM, INC. | 2012-03-15 | — | — | US | claimed |
| WO-2012018403-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM IP, LLC (US) | 2012-02-09 | — | — | WO | claimed |
| US-9175141-B2 | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof | BIOFILM IP, LLC (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2601245-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | Biofilm IP, LLC (US) | 2013-06-12 | — | — | EP | disclosed |
| US-20120064022-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM, INC. | 2012-03-15 | — | — | US | disclosed |
| WO-2012018403-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM IP, LLC (US) | 2012-02-09 | — | — | WO | disclosed |
| US-6836608-B2 | Planar optical waveguide, method for manufacturing the same and polymer optical waveguide | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| US-20020085825-A1 | Planar optical waveguide, method for manufacturing the same and polymer optical waveguide | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2002-07-04 | — | — | US | disclosed |