Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977552 | 0.84 | KDM4E (0.66) | KDM4EKMT2APIM1PSMD14COPS5 | |
| SCHEMBL13977541 | 0.82 | PIM1 (0.67) | KDM4EKMT2APIM1PSMD14COPS5 | |
| SCHEMBL1051386 | 0.80 | KDM4E (0.71) | KDM4EKMT2APIM1MMP2ALDH1A1 | |
| SCHEMBL6112866 | 0.80 | PARP1 (0.49) | KDM4EKMT2APIM1MMP2PARP1 | |
| SCHEMBL15865601 | 0.79 | KDM4E (0.44) | KDM4EKMT2APIM1MMP2PARP1 | |
| SCHEMBL341567 | 0.79 | BACE1 (0.50) | KDM4EKMT2APIM1PSMD14MMP2 | |
| SCHEMBL28932903 | 0.79 | PARP1 (0.47) | KDM4EKMT2APIM1MMP2PARP1 | |
| SCHEMBL17268386 | 0.77 | KDM4E (0.45) | KDM4EKMT2APIM1MMP2PARP1 | |
| Hydrochloric Acid SCHEMBL28339116 | 0.77 | PARP1 (0.46) | KDM4EKMT2APIM1MMP2PARP1 | |
| SCHEMBL30937996 | 0.76 | ALDH1A1 (0.47) | KDM4EKMT2APIM1MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| US-20080207673-A1 | Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins | XILINAS MICHEL | 2008-08-28 | — | — | US | claimed |
| WO-2006117660-A2 | METHOD FOR TREATING CANCER, CORONARY, INFLAMMATORY AND MACULAR DISEASE, COMBINING THE MODULATION OF ZINC- AND/OR COPPER DEPENDENT PROTEINS | CLIO PHARMACEUTICAL CORPORATION (US) | 2006-11-09 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20080207673-A1 | Method for Treating Cancer, Coronary, Inflammatory and Macular Disease, Combining the Modulation of Zinc-and/or Copper Dependent Proteins | XILINAS MICHEL | 2008-08-28 | — | — | US | disclosed |
| WO-2006117660-A2 | METHOD FOR TREATING CANCER, CORONARY, INFLAMMATORY AND MACULAR DISEASE, COMBINING THE MODULATION OF ZINC- AND/OR COPPER DEPENDENT PROTEINS | CLIO PHARMACEUTICAL CORPORATION (US) | 2006-11-09 | — | — | WO | disclosed |
| WO-2002051415-A2 | USE OF SEQUESTRANTS FOR TREATING PRION DISEASES | XILINAS MICHEL (CY) | 2002-07-04 | — | — | WO | disclosed |