SCHEMBL6112866

SCHEMBL6112866

CC(=O)c1ccc2cccc(C(C)=O)c2n1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.49
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
PIM1 P11309 1/20 0.46
MMP2 P08253 2/20 0.42
PDE4D Q08499 1/20 0.38
NPC1 O15118 1/20 0.38
CASP3 P42574 1/20 0.38
RAB9A P51151 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
MEN1 O00255 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TERT O14746 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28932903 0.98 PARP1 (0.47) PARP1KMT2AKDM4EPIM1MMP2
SCHEMBL15228552 0.85 CYP1A2 (0.44) PARP1KMT2AKDM4EPIM1MMP2
SCHEMBL1051386 0.81 KDM4E (0.71) KMT2AKDM4EPIM1MMP2PDE4D
SCHEMBL15228723 0.80 PARP1 (0.47) PARP1KMT2AKDM4EPIM1NPC1
SCHEMBL29103150 0.80 PARP1 (0.47) PARP1KMT2AKDM4ENPC1CASP3
SCHEMBL4459171 0.80 KDM4E (0.46) PARP1KMT2AKDM4EPIM1MMP2
SCHEMBL341567 0.80 BACE1 (0.50) PARP1KMT2AKDM4EPIM1MMP2
SCHEMBL17268386 0.79 KDM4E (0.45) PARP1KMT2AKDM4EPIM1MMP2
SCHEMBL3340090 0.78 ALDH1A1 (0.47) KMT2AKDM4EPIM1MMP2ALDH1A1
SCHEMBL30937996 0.78 ALDH1A1 (0.47) KMT2AKDM4EPIM1MMP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109701647-B Catalyst composition and application thereof 中国石油化工股份有限公司 2021-12-21 CN claimed
CN-107282120-B Catalyst composition for ethylene oligomerization and oligomerization method 中国石油化工股份有限公司 2019-12-24 CN claimed
CN-105566039-A Ethene oligomerization continuous reaction method CHINA PETROLEUM & CHEM CORP 2016-05-11 CN claimed
CN-109701647-B Catalyst composition and application thereof 中国石油化工股份有限公司 2021-12-21 CN disclosed
CN-107282120-B Catalyst composition for ethylene oligomerization and oligomerization method 中国石油化工股份有限公司 2019-12-24 CN disclosed
CN-107282120-B Catalyst composition for ethylene oligomerization and oligomerization method 中国石油化工股份有限公司 2019-12-24 CN disclosed
CN-109701647-A A kind of carbon monoxide-olefin polymeric and its application 中国石油化工股份有限公司 2019-05-03 CN disclosed
CN-105566039-B A kind of ethylene oligomerization continuous reaction method 中国石油化工股份有限公司 2018-05-11 CN disclosed
CN-105478165-B A kind of ethylene oligomerization carbon monoxide-olefin polymeric 中国石油化工股份有限公司 2017-12-19 CN disclosed
CN-107282120-A A kind of ethylene oligomerization carbon monoxide-olefin polymeric and oligomerization 中国石油化工股份有限公司 2017-10-24 CN disclosed
CN-105566039-A Ethene oligomerization continuous reaction method CHINA PETROLEUM & CHEM CORP 2016-05-11 CN disclosed
CN-105478165-A Catalyst composition for ethylene oligomerization CHINA PETROLEUM & CHEM CORP 2016-04-13 CN disclosed
CN-105478165-A Catalyst composition for ethylene oligomerization CHINA PETROLEUM & CHEM CORP 2016-04-13 CN disclosed
EP-2643335-B1 HYDROSILYLATION CATALYST MOMENTIVE PERFORMANCE MAT INC (US) 2015-03-11 EP disclosed
US-8637626-B2 Non-precious metal-containing 2,8-bis(imino)quinoline complexes and their use as hydrosilylation catalysts MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-01-28 US disclosed
CN-103347889-A Hydrosilylation catalysts MOMENTIVE PERFORMANCE MAT INC 2013-10-09 CN disclosed
EP-2643335-A1 HYDROSILYLATION CATALYST Momentive Performance Materials Inc. (US) 2013-10-02 EP disclosed
CN-102060852-B Quinoline complexes, preparation method thereof, quinoline complex-containing catalyst and use of catalyst in catalysis of vinyl polymerization CHINESE ACAD INST CHEMISTRY 2012-07-04 CN disclosed
WO-2012071359-A1 HYDROSILYLATION CATALYST MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-05-31 WO disclosed
US-20120130021-A1 NON-PRECIOUS METAL-CONTAINING 2,8-BIS(IMINO)QUINOLINE COMPLEXES AND THEIR USE AS HYDROSILYLATION CATALYSTS CORNELL UNIVERSITY (US) 2012-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130021-A1 NON-PRECIOUS METAL-CONTAINING 2,8-BIS(IMINO)QUINOLINE COMPLEXES AND THEIR USE AS HYDROSILYLATION CATALYSTS NQO1, NIT2, CIP2A PARP1 142/4885KMT2A 725/4885KDM4E 3450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.