Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462859 | 0.86 | PRMT5 (0.54) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4326934 | 0.82 | KDM4E (0.60) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4457837 | 0.82 | KDM4E (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL6445038 | 0.81 | KMT2A (0.63) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4453437 | 0.81 | KMT2A (0.63) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4327103 | 0.74 | MAPT (1.00) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4327099 | 0.74 | MAPT (1.00) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL4338798 | 0.72 | CYP2A6 (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL3649775 | 0.72 | HPGD (1.00) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL3649780 | 0.72 | HPGD (1.00) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |